glycamal®
glycamal®
General information about glycamal® (Glycerinformal):
- Glycamal offered by ALTEQO is based 100% on glycerol of natural, regenerative origin, obtained from GMO-free vegetable oils (87% of the final product Glycamal is of biogenic origin).
- Glycamal is safe during storage, production, application and disposal due to its low vapour pressure and it being neither flammable nor explosive.
- Glycamal stands out by its distinct hydrotropic character: it shows complete miscibility with water, DMA, DMF, DMSO and NMP, while being mixable with many fat oils, numerous alcohols, aldehydes, ketones, ethers, esters, aromatics and carbonates.
- According to calculated Hansen parameters, it has similar mixing properties as 1-propanol, ethanol, ethylene glycol, diethylene glycol, dipropylene glycol, dipropyleneglycol monomethyl ether, DMF, aniline and cresol.
- Glycamal is a clear, colourless, odourless liquid, that has a pH of 4.0 – 6.5 at 20 °C and shows exceedingly low evaporation.
- Glycamal shows high stability, even in acidic environment: neither autooxidation nor hydrolysis occur.
- Glycamal is neither acutely toxic, nor bioaccumulative or mutagenic. Beware of suspected fetotoxicity and teratogenicity when taken orally.
- Glycamal EP conforms the regulatory requirements of quality of the European Pharmacopoeia and can be used in pharmaceuticals.
glycamal® applications
- Glycasol is non-toxic, but shows limited stability in acidic environments. It is a suitable replacement for NMP (N-Methyl-2-pyrolidon) as solvent for neonicotinoids.
- Glycamal is stable also in acidic environments. Glycamal is a suitable replacement for mixtures including naphtha or solvent naphtha or NMP (N-Methyl-2-pyrolidon) in institutional plant protection (herbicides and fungicides).
Please contact our product experts to receive further information.
- Glycasol is used as dissolving agent or carrier in human pharma products for transdermal application. In topical compositions for acne treatment, it acts as water miscible solvent for solubilizing benzoyl peroxide and may also improve skin penetration of the benzoyl peroxide.
- Glycasol facilitates skin penetration of some active compounds (preferably hormones, but also immunomodulators, immunosuppressants, antibiotics, cytostatics, diuretics, gastrointestinal agents, cardiovascular agents and neuropharmaceuticals or mixtures thereof) and is therefore advantageous in transdermal therapeutic systems (TTS).
- Glycamal and Glycasol are both fully miscible with SAIB (sucrose acetate isobutyrate) and are therefore suitable solvents for application of biodegradable pharmaceutical systems for controlled release of medically active substances.
- Glycamal is commonly used as carrier or enhancers for multiple pharmaceutical compounds (i.e. avermectins, ivermectin) in veterinary applications for injectable products.
- Glycasol facilitates skin penetration of some active compounds (preferably hormones, but also immunomodulators, immunosuppressants, antibiotics, cytostatics, diuretics, gastrointestinal agents, cardiovascular agents and neuropharmaceuticals or mixtures thereof) and is therefore advantageous in transdermal therapeutic systems (TTS).
- Glycamal and Glycasol are both fully miscible with SAIB (sucrose acetate isobutyrate) and are therefore suitable solvents for application of biodegradable pharmaceutical systems for controlled release of medically active substances.
